Peter has the 24 hour flu when Doc Ock captures Betty Brant in hopes of luring Spider-Man into battle; Ock beats the under the weather web-head and unmasks him, but everyone thinks it is just Peter trying to be brave by impersonating Spidey; Once he has recovered, Spider-Man battles through the wild animals Ock has released from the zoo to take on old six-arms himself.
Printed: May 1964
Writers: Stan Lee
Art: Steve Ditko
Cover: Steve Ditko
- 3rd appearance of Dr. Octopus
- Reference to the creators of Spider-Man, Stan Lee and Steve Ditko are depicted on a sign advertising a fictional company called Leedit Inc. aka Lee Dit(Co.)
